Single-Molecule Study of Proteins by Biological Nanopore Sensors

نویسندگان

  • Dongmei Wu
  • Sheng Bi
  • Liyu Zhang
  • Jun Yang
چکیده

Nanopore technology has been developed for detecting properties of proteins through monitoring of ionic current modulations as protein passes via a nanosize pore. As a real-time, sensitive, selective and stable technology, biological nanopores are of widespread concern. Here, we introduce the background of nanopore researches in the area of α-hemolysin (α-HL) nanopores in protein conformation detections and protein-ligand interactions. Moreover, several original biological nanopores are also introduced with various features and functions.

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عنوان ژورنال:

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2014